Safety of Exercise Testing in the Clinical Chinese Population
Open Access
- 9 February 2021
- journal article
- research article
- Published by Frontiers Media SA in Frontiers in Cardiovascular Medicine
Abstract
This 18-year cross-sectional study was conducted to provide data on the safety of exercise testing in the clinical Chinese population. We retrospectively identified exercise tests completed at Xiangya Hospital of Central South University from January 1, 2002 to December 31, 2019. From 43,130 unique individuals (50.9% female), a total of consecutive 50,142 tests (standard exercise testing 29,466; cardiopulmonary exercise testing 20,696) were retrieved. Demographics, patients' medical history, exercise testing characteristics, and exercise testing-related adverse events were described. Safety data is expressed as the number of adverse events per 10,000 tests, with 95% confidence interval. The average patients' age was 51 ± 13 years. The majority of patients were diagnosed with at least one disease (N = 44,941, 89.6%). Tests were maximal or symptom-limited. Common clinical symptoms included dizziness (6,822, 13.6%), chest pain or distress (2,760, 5.5%), and musculoskeletal limitations (2,507, 5.0%). Out of 50,142 tests, three adverse events occurred, including one sustained ventricular tachycardia, one sinus arrest with junctional escape rhythm at a rate of 28 bpm, and one syncopal event with fecal and urinary incontinence. The rate of adverse events was 0.8 events per 10,000 tests (95% confidence interval, 0.2–3.0) in men, 0.4 per 10,000 tests (0.7–2.2) in women, and 0.6 per 10,000 tests (0.21.8) total. This study represents the largest dataset analysis of exercise testing in the clinical Chinese population. Our results demonstrate that clinical exercise testing is safe, and the low rate of adverse events related to exercise testing might be due to the overall changes in clinical practice over time.This publication has 29 references indexed in Scilit:
- Exercise Standards for Testing and TrainingCirculation, 2013
- The Safety of Cardiopulmonary Exercise Testing in a Population With High-Risk Cardiovascular DiseasesCirculation, 2012
- Early exercise stress testing is safe after primary percutaneous coronary interventionEuropean Heart Journal Acute Cardiovascular Care, 2012
- Safety of symptom-limited cardiopulmonary exercise testing in patients with chronic heart failure due to severe left ventricular systolic dysfunctionAmerican Heart Journal, 2009
- Safety and diagnostic accuracy of stress cardiac magnetic resonance imaging vs exercise tolerance testing early after acute ST elevation myocardial infarctionHeart, 2007
- Exercise Standards for Testing and TrainingCirculation, 2001
- EXERCISE TESTING IN CARDIAC REHABILITATIONCardiology Clinics, 2001
- The safety of maximal exercise testing.Circulation, 1989
- Lebensbedrohliche Komplikationen bei 1741106 ErgometrienDeutsche Medizinische Wochenschrift (1946), 1984
- Exercise tests. A survey of procedures, safety, and litigation experience in approximately 170,000 testsJAMA, 1971