Effect of Dietary Lactobacillus casei on Physiometabolic Responses and Liver Histopathology in Common Carp (Cyprinus carpio) After Exposure to Iron Oxide Nanoparticles
- 30 August 2021
- journal article
- research article
- Published by Springer Science and Business Media LLC in Biological Trace Element Research
- Vol. 200 (7), 3346-3354
- https://doi.org/10.1007/s12011-021-02906-9
Abstract
A 60-day feeding trial was performed to assess the dietary effect of Lactobacillus casei as a probiotic supplement on some serum biochemical parameters and liver histopathology in common carp fry after exposure to iron oxide nanoparticles (IoNPs). Six treatments were prepared as follows: control (no IoNP exposure and no dietary probiotic), P6: 106 CFU/g probiotic diet, P7: 107 CFU/g probiotic diet, NPs: 0.15 mg/l IoNPs, NPs + P6: 0.15 mg/l IoNPs with 106 CFU/g probiotic diet, and NPs + P7: 0.15 mg/l IoNPs with 107 CFU/gprobiotic diet. Based on the results, serum aspartate aminotransferase and alanine aminotransferase levels were significantly increased in 0.15 mg/l IoNPs, P7, and NPs + P6 treatments compared to the control group. In addition, the examination of antioxidant enzymes showed a significant increase in the levels of cortisol and glutathione S-transferase as well as malondialdehyde level. IoNPs also caused significant histopathological changes in the fish liver during the experiment such as hyperemia in sinusoidal spaces, hepatocytes vacuolation and necrosis, pyknosis, and disruption of hepatic lobules and atrophy. Results revealed the protective effects of dietary L. casei to mitigate the adverse impacts of IoNPs on the physiological processes of common carp.Keywords
This publication has 63 references indexed in Scilit:
- Toxicity of Citrate-Capped Silver Nanoparticles in Common Carp (Cyprinus carpio)Journal of Biomedicine and Biotechnology, 2012
- Toxicity Assessment of Iron Oxide Nanoparticles in Zebrafish (Danio rerio) Early Life StagesPLOS ONE, 2012
- Association of High Blood Pressure with Renal Insufficiency: Role of Albuminuria, from NHANES, 1999–2006PLOS ONE, 2012
- Sorption kinetic study of selenite and selenate onto a high and low pressure aged iron oxide nanomaterialJournal of Hazardous Materials, 2012
- Trends in Tissue Engineering for Blood VesselsJournal of Biomedicine and Biotechnology, 2012
- Adsorption and desorption of bivalent metals to hematite nanoparticlesEnvironmental Toxicology and Chemistry, 2011
- Physiological effects of nanoparticles on fish: A comparison of nanometals versus metal ionsEnvironment International, 2011
- Recent Advances in Nanotechnology Applied to BiosensorsSensors, 2009
- Siderophore-Based Iron Acquisition and Pathogen ControlMicrobiology and Molecular Biology Reviews, 2007
- Effects of selenium on histopathological and enzymatic changes in experimental liver injury of ratsExperimental and Toxicologic Pathology, 2004