Detoxifying deoxynivalenol (DON)-contaminated feedstuff: consequences of sodium sulphite (SoS) treatment on performance and blood parameters in fattening pigs
Open Access
- 1 May 2020
- journal article
- research article
- Published by Springer Science and Business Media LLC in Mycotoxin Research
- Vol. 36 (2), 213-223
- https://doi.org/10.1007/s12550-019-00385-5
Abstract
A 10-week feeding experiment was carried out examining the effects of deoxynivalenol (DON)-contaminated maize treated with different sodium sulphite (SoS) concentrations on performance, health and DON-plasma concentrations in fattening pigs. Two maize batches were used: background-contaminated (CON, 0.73 mg/kg maize) and Fusarium-toxin contaminated (DON, 44.45 mg/kg maize) maize. Both were wet preserved at 20% moisture content, with one of three (0.0, 2.5, 5.0 g/kg maize) sodium sulphite concentrations and propionic acid (15%). Each maize batch was then mixed into a barley-wheat-based diet at a proportion of 10%, resulting in the following 6 feeding groups: CON- (CON + 0.0 g SoS/kg maize), CON2.5 (CON + 2.5 g SoS/kg maize), CON5.0 (CON + 5.0 g SoS/kg maize), DON- (DON + 0.0 g SoS/kg maize), DON2.5 (DON + 2.5 g SoS/kg maize) and DON5.0 (DON + 5.0 g SoS/kg maize). Dietary DON concentration was reduced by ~ 36% in group DON2.5 and ~ 63% in group DON5.0. There was no impact on ZEN concentration in the diets due to SoS treatment. Pigs receiving diet DON- showed markedly lower feed intake (FI) compared to those fed the control diets. With SoS-treatment of maize, FI of pigs fed the DON diet (DON5.0: 3.35 kg/d) were comparable to that control (CON-: 3.30 kg/day), and these effects were also reflected in live weight gain. There were some effects of SoS, DON or their interaction on serum urea, cholesterol and albumin, but always within the physiological range and thus likely negligible. SoS wet preservation of Fusarium-toxin contaminated maize successfully detoxified DON to its innocuous sulfonates, thus restoring impaired performance in fatteners.Funding Information
- Friedrich-Loeffler-Institut, Bundesforschungsinstitut für Tiergesundheit
This publication has 27 references indexed in Scilit:
- Effects of oral exposure of pigs to deoxynivalenol (DON) sulfonate (DONS) as the non-toxic derivative of DON on tissue residues of DON and de-epoxy-DON and on DONS blood levelsFood Additives & Contaminants: Part A, 2010
- Decontamination and detoxification strategies for theFusariummycotoxin deoxynivalenol in animal feed and the effectiveness of microbial biodegradationFood Additives & Contaminants: Part A, 2010
- Chemical and biological transformations for detoxification of trichothecene mycotoxins in human and animal food chains: a reviewTrends in Food Science & Technology, 2010
- Effects of aFusariumtoxin-contaminated triticale, either untreated or treated with sodium metabisulphite (Na2S2O5, SBS), on weaned piglets with a special focus on liver function as determined by the13C-methacetin breath testArchives of Animal Nutrition, 2008
- Deoxynivalenol: Toxicity, mechanisms and animal health risksAnimal Feed Science and Technology, 2007
- Bioavailability of the Fusarium toxin deoxynivalenol (DON) from naturally contaminated wheat for the pigToxicology Letters, 2006
- On the effects of a hydrothermal treatment of deoxynivalenol (DON)-contaminated wheat in the presence of sodium metabisulphite (Na2S2O5) on DON reduction and on piglet performanceAnimal Feed Science and Technology, 2005
- Detoxification of deoxynivalenol with sodium bisulfite and evaluation of the effects when pure mycotoxin or contaminated corn was treated and given to pigsJournal of Agricultural and Food Chemistry, 1987
- Reduction in levels of deoxynivalenol in contaminated corn by chemical and physical treatmentJournal of Agricultural and Food Chemistry, 1986
- The toxicity of sulphite. I. Long-term feeding and multigeneration studies in ratsFood and Cosmetics Toxicology, 1972