Phytochemical screening of the medicinal plants reveals, very important and vital phytochemicals like tanins, saponin, flavonoids, Terpenoids and/or Stroids, alkaloids and anthraquinones, at a very appreciable quantity. In this study aims to assess the phytochemicals screening for ethanolic extracts of Boscia senegalensis, Cymbopogom schoenanthus, Hydnora abysinica and Rhynchosia minima., from the Sudan. The results showed the phytochemical screening revealed the presence of tannins, saponins, flavonoids, terpenoids and/or stroids, alkaloids and anthraquinones, in all plants, expect tannins (Boscia senegalensis), saponins (Hydnora abysinica), flavonoids (Cymbopogom schoenanthus), terpenoids and/or Stroids (Boscia senegalensis and Rhynchosia minima.,) and alkaloids (Cymbopogom schoenanthus). However, we can see a phytochemical screening harvested in all plants ethanolic extracts highlighted in this study could justify the traditional uses of this plant in the treatment of several pathologies.