Ocular Motor and Vestibular Disorders in Brainstem Disease
- 1 November 2019
- journal article
- review article
- Published by Ovid Technologies (Wolters Kluwer Health) in Journal of Clinical Neurophysiology
- Vol. 36 (6), 396-404
- https://doi.org/10.1097/wnp.0000000000000593
Abstract
The brainstem contains ocular motor and vestibular structures that, when damaged, produce specific eye movement disorders. In this review, we will discuss three brainstem syndromes with characteristic ocular motor and vestibular findings that can be highly localizing. First, we will discuss the lateral medullary (Wallenberg) syndrome, focusing on ocular lateropulsion, saccadic dysmetria, and the ocular tilt reaction. Second, we will review the medial longitudinal fasciculus syndrome including the ocular tilt reaction, nystagmus, and the vestibular-ocular reflex. Lastly, we will discuss hypertrophic olivary degeneration and oculopalatal tremor, which may develop weeks to months after a brainstem or cerebellar lesion. In these syndromes, the clinical ocular motor and vestibular examination is instrumental in localizing the lesion.Keywords
This publication has 77 references indexed in Scilit:
- Hypertrophic olivary degeneration following surgical resection or gamma knife radiosurgery of brainstem cavernous malformations: an 11-case series and a review of literatureActa Neurochirurgica, 2012
- Pharmacological tests of hypotheses for acquired pendular nystagmusAnnals of the New York Academy of Sciences, 2011
- Crossover trial of gabapentin and memantine as treatment for acquired nystagmusAnnals of Neurology, 2010
- Oculopalatal tremor explained by a model of inferior olivary hypertrophy and cerebellar plasticityBrain, 2010
- HINTS to Diagnose Stroke in the Acute Vestibular SyndromeStroke, 2009
- Head-shaking nystagmus in lateral medullary infarctionNeurology, 2007
- Patterns of ocular oscillation in oculopalatal tremorNeurology, 2007
- Progressive ataxia and palatal tremor (PAPT): Clinical and MRI assessment with review of palatal tremorsBrain, 2004
- Palatal myoclonus--its remote influence.Journal of Neurology, Neurosurgery & Psychiatry, 1984
- Demyelinating disease presenting as Wallenberg's syndrome. Report of a patient.Stroke, 1981