Genetic Heterogeneity of Australian Candida auris Isolates: Insights From a Nonoutbreak Setting Using Whole-Genome Sequencing

Abstract

Whole genome sequencing clustered Australian Candida auris isolates from sporadic cases within clade III. Case isolates were genomically distinct; however, unexpectedly, those from one case comprised two groups separated by >60 single nucleotide polymorphisms (SNPs) with no isolate being identical in contrast to outbreaks where isolates from any one individual have differed by C. auris infections.