An effective polymeric nanocarrier that allows for active targeting and selective drug delivery in cell coculture systems

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Abstract
A versatile and robust approach for active targeted delivery based on the use of antibody-decorated nanoparticles offering remarkable discrimination efficiency between cocultured cells with different expression levels of a specific marker has been developed.
Funding Information
  • Agencia Estatal de Investigación (RED2018-102469-T)
  • Instituto de Salud Carlos III (DTS18/00121)
  • Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía (B-FQM-475-UGR18, PT18-TP-1490 and AT17_6096)
  • Ministerio de Educación y Cultura (FPU 16/02061)
  • Secretaría de Estado de Investigación, Desarrollo e Innovación (PTQ-16- 08597)