A Multicenter Study of the Prevalence of Dry Eye Disease in Chinese Refractive Surgery Candidates
- 2 June 2020
- journal article
- research article
- Published by S. Karger AG in Ophthalmic Research
- Vol. 64 (2), 224-229
- https://doi.org/10.1159/000509060
Abstract
Objective: To determine the prevalence of preoperative dry eye disease and evaluate tear film function in refractive surgery candidates in China. Methods: In this prospective noninterventional cross-sectional study, refractive surgical candidates from 13 pre-selected eye hospitals in China were recruited from July 2015 to February 2016. Patient histories, subjective symptoms, tear film breakup time (TBUT), ocular surface fluorescein staining, and Schirmer I tests (SIT), were assessed to conduct subgroup analysis. Results: A total of 1849 patients were recruited, 41.4% were diagnosed with dry eye disease (766/1849) and 44.9% (830/1849) of subjects had a positive history of contact lens wear. The overall mean TBUT and SIT values were 7.3 ± 3.7s and 15.2 ± 8.8mm, respectively. The total prevalence of ocular surface fluorescein staining was 23.46% (422/1849). 44.62% of patients had TBUT <5s, 23.20% of patients had SIT <5mm. Contact lens wearers were observed to have a higher prevalence of dry eye than non-contact lens wearers (54.1% vs 35.2%, OR=2.17, 95%CI: 1.77-2.65). Conclusions: In this study, the most common abnormal finding in dry eye disease was tear film instability. A high proportion of refractive surgery candidates have preexisting dry eye disease and a history of contact-lens wear prior to surgery. Careful attention should be given to the evaluation of preoperative dry eye in refractive surgery candidates.Keywords
This publication has 20 references indexed in Scilit:
- Prevalence of and Risk Factors for Dry Eye Symptom in Mainland China: A Systematic Review and Meta-AnalysisJournal of Ophthalmology, 2014
- Tear Function Evaluation in Candidates of Corneal Laser Refractive Surgery for MyopiaEye & Contact Lens: Science & Clinical Practice, 2014
- Assessment of Vision-Related Quality of Life in Dry Eye PatientsInvestigative Ophthalmology & Visual Science, 2012
- Post-LASIK dry eyeExpert Review of Ophthalmology, 2011
- In Vivo Confocal Microscopy of Meibomian Glands in Contact Lens WearersInvestigative Ophthalmology & Visual Science, 2011
- Dry eyes and corneal sensation after laser in situ keratomileusis with femtosecond laser flap creationJournal of Cataract & Refractive Surgery, 2009
- Dry eye associated with laser in situ keratomileusis: Mechanical microkeratome versus femtosecond laserJournal of Cataract & Refractive Surgery, 2009
- Aggravated Dry Eye After Laser In Situ Keratomileusis in Patients With Sjögren SyndromeCornea, 2008
- Refractive surgery in the United States Army, 2000–2003Ophthalmology, 2005
- Chronic dry eye and regression after laser in situ keratomileusis for myopiaJournal of Cataract & Refractive Surgery, 2004