Creation of a severity index for hidradenitis suppurativa that includes a validated quality-of-life measure: the HIDRAscore
Open Access
- 1 August 2020
- journal article
- research article
- Published by Wiley in Journal of the European Academy of Dermatology and Venereology
- Vol. 34 (8), 1815-1821
- https://doi.org/10.1111/jdv.16328
Abstract
Background Hidradenitis suppurativa (HS) is a chronic, debilitating disease with a considerable effect on patient quality of life. Its clinical severity can be measured using different scoring systems; however, few of them include patient-centred parameters. Objective To create a new scoring system for HS that includes a quality-of-life instrument, the HIDRAdisk. Methods This post hoc analysis was carried out within the framework of a multicentre, longitudinal, epidemiologic study conducted over 9 months on quality-of-life aspects of HS. The new severity score was created using as reference a question from the Subject Satisfaction Questionnaire (SSQ) concerning the severity of HS as evaluated by the patient. Associated variables were selected using univariable and multivariable logistic regression models. The discriminant capabilities of the final model and of the final score were evaluated by the area under the receiver operating characteristic curve and the Hosmer-Lemeshow test. Results The study population included 308 patients with HS of any severity grade. According to the results of the regression models, the variables associated with the reference SSQ measure were number of inflammatory nodules, abscesses and draining fistulas; the HIDRAdisk score; and the number of subumbilical lesions. The HIDRAscore is obtained by the sum of the scores associated with the number of these parameters. Possible scores range from 0 to 10. Conclusion The HIDRAscore is a new scoring system for HS severity which, in addition to the clinical evaluation by the physician, includes a validated patient-reported outcome measure, the HIDRAdisk.Funding Information
- AbbVie
This publication has 24 references indexed in Scilit:
- Quality-of-Life Impairment in Patients with Hidradenitis Suppurativa: A Canadian StudyAmerican Journal of Clinical Dermatology, 2014
- Assessing the validity, responsiveness and meaningfulness of the Hidradenitis Suppurativa Clinical Response (HiSCR) as the clinical endpoint for hidradenitis suppurativa treatmentBritish Journal of Dermatology, 2014
- Incidence of Hidradenitis Suppurativa and Associated Factors: A Population-Based Study of Olmsted County, MinnesotaJournal of Investigative Dermatology, 2013
- Adalimumab for the Treatment of Moderate to Severe Hidradenitis SuppurativaAnnals of Internal Medicine, 2012
- Bedside prediction rule for infections after pediatric cardiac surgeryIntensive Care Medicine, 2012
- Physician Communication and Patient Adherence to TreatmentMedical Care, 2009
- Quality of life impairment in hidradenitis suppurativa: A study of 61 casesJournal of the American Academy of Dermatology, 2007
- Measures of Clinical Severity, Quality of Life, and Psychological Distress in Patients with Psoriasis: A Cluster AnalysisJournal of Investigative Dermatology, 2004
- Health-Related Quality-of-Life Assessments and Patient-Physician CommunicationJAMA, 2002
- Assessing the Effects of Physician-Patient Interactions on the Outcomes of Chronic DiseaseMedical Care, 1989