Resolution of Disseminated Intravascular Coagulation in a Patient with COVID-19 and Associated Sepsis—Induced Neutropenia
Open Access
- 24 January 2021
- Vol. 57 (2), 106
- https://doi.org/10.3390/medicina57020106
Abstract
COVID-19 has been associated with a hypercoagulable state and thrombotic events. Venous thromboembolism has been the most commonly reported type of thrombosis but also arterial thrombosis and disseminated intravascular coagulation in inpatients have been described frequently in several clinical experiences. Patients with COVID-19, because of its tendency to induce leucopenia and overlapping of bacterial infection, may experience sudden disseminated intravascular coagulation (DIC), as in the case that we report here. However, early diagnosis and treatment may be associated with positive resolution of these severe complications.Keywords
This publication has 18 references indexed in Scilit:
- DIC in COVID‐19: Implications for prognosis and treatment?Journal of Thrombosis and Haemostasis, 2020
- COVID-19, ECMO, and lymphopenia: a word of cautionThe Lancet Respiratory Medicine, 2020
- Disseminated intravascular coagulation: an update on pathogenesis and diagnosisExpert Review of Hematology, 2018
- Neutropenic FeverHematology/Oncology Clinics of North America, 2017
- Risks for infection in patients with myelodysplasia and acute leukemiaCurrent Opinion in Infectious Diseases, 2012
- Infections in myelodysplastic syndromesHaematologica, 2012
- Sepsis, thrombosis and organ dysfunctionThrombosis Research, 2012
- Hyperproduction of fibrin and inefficacy of antithrombin III and α2 macroglobulin in the presence of bacterial porinsInternational Journal of Experimental Pathology, 2005
- Porins from Salmonella typhimurium accelerate human blood coagulation in vitro by selective stimulation of thrombin activity: implications in septic shock DIC pathogenesisInnate Immunity, 2001
- Porins from Salmonella typhimurium accelerate human blood coagulation in vitro by selective stimulation of thrombin activity: implications in septic shock DIC pathogenesisInnate Immunity, 2001