Prevalence and clinical significance of the MYD88 (L265P) somatic mutation in Waldenström’s macroglobulinemia and related lymphoid neoplasms
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Open Access
- 28 March 2013
- journal article
- Published by American Society of Hematology in Blood
- Vol. 121 (13), 2522-2528
- https://doi.org/10.1182/blood-2012-09-457101
Abstract
Key Points Using a sensitive method, the MYD88 (L265P) mutation is detectable in all patients with Waldenström’s macroglobulinemia, therefore representing a hallmark of the disease. MYD88 (L265P) is also found in a substantial proportion of patients with IgM-MGUS.This publication has 31 references indexed in Scilit:
- Simple genetic diagnosis of hairy cell leukemia by sensitive detection of the BRAF-V600E mutationBlood, 2012
- Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractorinessBlood, 2011
- Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemiaNature Genetics, 2011
- BRAFMutations in Hairy-Cell LeukemiaThe New England Journal of Medicine, 2011
- Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemiaNature, 2011
- Initial genome sequencing and analysis of multiple myelomaNature, 2011
- Differential characteristics of Waldenström macroglobulinemia according to patterns of familial aggregationBlood, 2010
- Risk of lymphoproliferative disorders among first-degree relatives of lymphoplasmacytic lymphoma/Waldenström macroglobulinemia patients: a population-based study in SwedenBlood, 2008
- Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencingNature Genetics, 2008
- Characterization of familial Waldenström's macroglobulinemiaAnnals of Oncology, 2005