Retinal blood flow reduction in normal-tension glaucoma with single-hemifield damage by Doppler optical coherence tomography
- 26 March 2020
- journal article
- research article
- Published by BMJ in British Journal of Ophthalmology
- Vol. 105 (1), 124-130
- https://doi.org/10.1136/bjophthalmol-2019-315616
Abstract
Aims To evaluate the associations between retinal blood flow (RBF) and optical coherence tomography (OCT) structural measurements in normal-tension glaucoma (NTG) eyes with single-hemifield visual field (VF) damage by the Doppler OCT. Methods The Doppler OCT was used to measure temporal artery (TA) RBF and temporal vein (TV) RBF. Retinal nerve fibre layer thickness (RNFLT) was measured by spectral-domain OCT. Results Forty-three consecutive eyes of 43 patients with NTG with VF defect confined to a single hemifield and 24 eyes of 24 age-matched healthy subjects were studied. TA and TV RBF and RNFLT were reduced in the damaged hemisphere compared with the normal hemisphere (mean (SD), 3.61 (1.68) vs 5.86 (2.59) µL/min, pConclusion In NTG eyes with single-hemifield damage, the RBF was significantly reduced in the damaged hemisphere compared with the normal one. The RBF decreased in the normal and damaged hemispheres of NTG eyes compared with the healthy hemisphere independent from RNFLT.Keywords
Funding Information
- JSPS KAKENHI (Grant Number: 16k20296)
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