Primary synchronous rectal squamous cell carcinoma and its exceptional response to chemoradiotherapy

Abstract

A 51-year-old female presented with rectal bleeding and anal pain. A colonoscopy was performed revealing a large lesion in the middle and lower rectum. These findings were confirmed on the CT scan. Nevertheless, the histopathological analysis revealed a more uncommon synchronous squamous cell carcinoma. Thus, due to the histology, pelvic radiotherapy with concurrent chemotherapy was administered.