Embryonal Rhabdomyosarcoma of the Biliary Tree as a Differential in a Paediatric Patient Presenting with Biliary Dilatation: Not Always a Choledochal Cyst
Open Access
- 24 January 2022
- journal article
- Published by Vilnius University Press in Acta medica Lituanica
- Vol. 29 (1), 2
- https://doi.org/10.15388/amed.2021.29.1.2
Abstract
Rhabdomyosarcoma is a soft tissue malignant musculoskeletal tumour and is the most prevalent soft-tissue sarcoma in the paediatric population. Although, Embryonal RMS of the biliary tree is a rare entity, however, it is the most common cause of paediatric malignant obstructive jaundice. We present a 4-year-old child who had symptoms of obstructive jaundice and palpable liver. The non-contrast magnetic resonance imaging and magnetic resonance cholangiopancreatography (MRCP) features were consistent with choledochal cyst. However, contrast enhanced computed tomography and PET CT images revealed biliary RMS as the differential diagnosis. Percutaneous biopsy followed by histopathology confirmed the diagnosis of embryonal biliary RMS. Since embryonal rhabdomyosarcoma is uncommonly recorded in the literature and can mimic the appearance of a choledochal cyst, this case report emphasises the necessity of keeping embryonal RMS as a differential in paediatric cases of obstructive jaundice.Keywords
This publication has 6 references indexed in Scilit:
- Embryonal rhabdomyosarcoma of the biliary tree in a paediatric patient – A rare cause of obstructive jaundiceSouth African Journal of Radiology, 2019
- Pediatric Anaplastic Embryonal Rhabdomyosarcoma: Targeted Therapy Guided by Genetic Analysis and a Patient-Derived Xenograft StudyFrontiers in Oncology, 2018
- Embryonal rhabdomyosarcoma of the biliary tree: A rare cause of obstructive jaundice in children which can mimic choledochal cystsIndian Journal of Radiology and Imaging, 2017
- The World Health Organization Classification of Skeletal Muscle Tumors in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology GroupArchives of Pathology & Laboratory Medicine, 2015
- Rhabdomyosarcoma of Biliary Tract— a Diagnostic DilemmaIndian Journal of Surgical Oncology, 2012
- Biliary rhabdomyosarcomaPediatric Radiology, 2007