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Assessment of Coronary Slow Flow, Cystatin C, and Body Mass Index in Female Candidates for Diagnostic Coronary Artery Angiography

Naser Aslan Abadi, Roghaiyeh Afsargharehbagh, Aliakbar Nasiri, Mirhosein Seyedmohammadzad, Kamal Khademvatan, Sima Ghaemimirabad, Abbas Malandish
International Journal of Basic Science in Medicine , Volume 5, pp 4-8; doi:10.34172/ijbsm.2020.03

Abstract: Introduction: Evidence indicates that the associations between coronary slow flow (CSF), cystatin C (Cys C), and body mass index (BMI) are unclear. Therefore, the purpose of our study was to determine the association among the above-mentioned parameters in female patients. Methods: This was a descriptive-analytical study and the participants were those who were referred to the Shohada Cardiovascular Center of Urmia in 2015-2016. The participants were measured by a quantitative method under angiography (corrected TIMI frame count, CTFC) for CSF assessment, followed by evaluating physiological indices and the serum Cys C by the enzyme-linked immunosorbent assay. Finally, Pearson correlation coefficient test was used to analyze the correlations among CTFC, Cys C, and BMI, and a significance level of P < 0.05 was used for this test. Results: Sixty-six female patients (mean age: 57.01±8.25 years) took part in this study. The correlations among Cys C with CTFC, and BMI (r=-0.189, P=0.128 and r=0.044, P=0.724, respectively) and BMI with CTFC (r=-0.178, P=0.153) were not meaningful in female patients’ who were candidates for angiography. Conclusion: In general, the results suggested that serum Cys C cannot be considered as a predictive biomarker for the prognostic stratification of CSF and BMI in female patients aged 34-73 years who were candidates for angiography.
Keywords: BMI / Angiography / CSF / flow / CYSTATIN / coronary / Candidates / Female Patients / Ctfc

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