Translation, validation and psychometric evaluation of the Persian (Farsi) version of the Low Anterior Resection Syndrome Score (LARS-P)
Open Access
- 25 February 2021
- journal article
- research article
- Published by Public Library of Science (PLoS) in PLOS ONE
- Vol. 16 (2), e0247054
- https://doi.org/10.1371/journal.pone.0247054
Abstract
Low anterior resection (LAR) for rectal cancer affects bowel function after the operation, causing a group of symptoms known as LAR Syndrome (LARS). LARS score is a patient-reported questionnaire to assess bowel dysfunction after the LAR operation. This study performed to validate the Persian (Farsi) translation of the LARS score and to investigate the psychometric properties of the score. The impact of LARS on the Quality of Life (QoL) of patients was also assessed. The LARS score was translated into Persian. Participants with a history of rectal cancer and low anterior resection were asked to complete the LARS score questionnaire. They were also asked a single question evaluating the impact of bowel function on QoL. Discriminative validity, convergent validity, sensitivity, and specificity of the questionnaire were calculated. A group of patients completed the score twice to assess the reliability of the questionnaire. From 358 patients with rectal cancer, 101 participants completed the Persian questionnaire. Answers of a high fraction of participants showed a moderate/perfect fit between their LARS score and their QoL. The Persian score demonstrated good convergent validity. It was able to differentiate between participants in terms of gender and T staging of the primary tumor. The score had high reliability. The Persian translation of the LARS score has excellent psychometric properties compared to previous translations in other languages. Therefore, it is a valid and reliable questionnaire to assess LARS.This publication has 26 references indexed in Scilit:
- Timing of Surgery After Long-Course Neoadjuvant Chemoradiotherapy for Rectal CancerDiseases of the Colon & Rectum, 2013
- A review on functional results of sphincter-saving surgery for rectal cancer: the anterior resection syndromeUpdates in Surgery, 2013
- Anterior resection syndromeThe Lancet Oncology, 2012
- Low Anterior Resection Syndrome ScoreAnnals of Surgery, 2012
- The Development of a Validated Instrument to Evaluate Bowel Function After Sphincter-Preserving Surgery for Rectal CancerDiseases of the Colon & Rectum, 2005
- Principles of Good Practice for the Translation and Cultural Adaptation Process for Patient-Reported Outcomes (PRO) Measures: Report of the ISPOR Task Force for Translation and Cultural AdaptationValue in Health, 2005
- Patient and surgeon ranking of the severity of symptoms associated with fecal incontinenceDiseases of the Colon & Rectum, 1999
- Prospective comparison of faecal incontinence grading systemsGut, 1999
- Etiology and management of fecal incontinenceDiseases of the Colon & Rectum, 1993
- Development of an electrically stimulated neoanal sphincterThe Lancet, 1991