COVID-19: What type of cytokine storm are we dealing with?

Abstract
We read with great interest the comment published by Andrianopoulos et al. in which the authors advocate for cautious use of tocilizumab in COVID‐19 patients 1. Tocilizumab is a monoclonal antibody against the interleukin‐6 receptor which has immunosuppressive properties. Whereas accumulating results from uncontrolled trials present tocilizumab as an effective agent blocker of disease progression, some contrasting studies also progressively appear in COVID‐19 literature 2‐5. This muddies the waters and makes the situation more confused.