The Cancer-Associated ATM R3008H Mutation Reveals the Link between ATM Activation and Its Exchange
Open Access
- 25 November 2020
- journal article
- research article
- Published by American Association for Cancer Research (AACR) in Cancer Research
- Vol. 81 (2), 426-437
- https://doi.org/10.1158/0008-5472.can-20-2447
Abstract
This study functionally characterizes the most common ATM missense mutation R3008H in cancer and identifies a unique role of PI3-kinase regulatory domain in ATM activation.Other Versions
Funding Information
- NIH NCI (R01CA158073, R01CA215067, R01CA226852, P01 CA174653)
- NIH NCI (T32 CA09503-29)
- NIH (NS-37956, CA-21765)
- CCSG (P30 CA21765)
- NIH (GM102362)
- NIH NCI (P30CA013696)
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