STUDY OF ALBUMIN, CALCIUM AND ALBUMIN CORRECTED CALCIUM WITH SEVERITY OF ACUTE PANCREATITIS
- 15 September 2021
- journal article
- Published by World Wide Journals
Abstract
Aim: The purpose of this study to evaluate the level of serum Albumin, Calcium and Albumin corrected calcium with severity of acute pancreatitis. Material and methods:The study was conducted in Department of Biochemistry in association with Department of Gastroenterology, Mahatma Gandhi Medical College & Hospital. In present study out of 133 patients diagnosed for Acute Pancreatitis; total 115 patients (n=115) of either gender of 18 to 65years age groups were enrolled for the study. Patients with history of any acute or chronic illness like: - Hyperparathyroidism, Diabetes Mellitus, Impaired renal function, Malnourished, Pregnant and lactating women and patients on calcium supplements were excluded. Result: Mean level of calcium decreased with progression in disease severity (p≤0.001).The mean Albumin Corrected Calcium was also signicantly lower in the patients presenting with severe and moderate acute pancreatitis compared with the mild acute pancreatitis patients (p≤0.0001). Conclusion: The study recommends hypocalcaemia and hypoalbuminemia as independent risk factors of progression towards severe pancreatitis. Similarly, albumin corrected calcium is suggested as a reliable marker for severity of pancreatitis.Keywords
This publication has 12 references indexed in Scilit:
- Prediction of Severity of Acute Pancreatitis Using Total Serum Calcium and Albumin-Corrected Calcium: A Prospective Study in Tertiary Center Hospital in NepalSurgery Research and Practice, 2017
- Serum Albumin Is Independently Associated with Persistent Organ Failure in Acute PancreatitisCanadian Journal of Gastroenterology and Hepatology, 2017
- Calcium signaling of pancreatic acinar cells in the pathogenesis of pancreatitisWorld Journal of Gastroenterology, 2014
- Total serum calcium and corrected calcium as severity predictors in acute pancreatitisRevista de Gastroenterología de México (English Edition), 2014
- Classification of acute pancreatitis—2012: revision of the Atlanta classification and definitions by international consensusGut, 2012
- A Conservative and Minimally Invasive Approach to Necrotizing Pancreatitis Improves OutcomeGastroenterology, 2011
- Practice Guidelines in Acute PancreatitisThe American Journal of Gastroenterology, 2006
- Serum calcium measurement: Total versus free (ionized) calciumIndian Journal of Clinical Biochemistry, 2005
- Death due to acute pancreatitisDigestive Diseases and Sciences, 1985
- Serum ionized calcium in acute pancreatitisBritish Journal of Surgery, 1977