Serum Inflammation Biomarkers in Patients with Keratoconus
- 18 August 2021
- journal article
- research article
- Published by Informa UK Limited in Ocular Immunology and Inflammation
- Vol. 29 (6), 1164-1167
- https://doi.org/10.1080/09273948.2020.1741648
Abstract
Purpose: To evaluate inflammation-sensitive parameters, namely the neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), eosinophil count, erythrocyte distribution width (RDW), and CRP/albumin ratio in patients with keratoconus (KC). Methods: Thirty-five patients with KC and 30 healthy people (control group) were included in the study. Complete blood count measurements were performed in all subjects, and NLR, PLR and the CRP/albumin ratio were calculated. Results: NLR was determined as 2.01 +/- 0.53 in patients with KC and 1.97 +/- 0.41 in the control group. PLR was 146.20 +/- 23.32 in the KC group and 121.45 +/- 31.75 in the healthy group. The CRP/albumin ratio was determined as 0.33 +/- 0.09 in the KC group and 0.29 +/- 0.11 in the healthy group. Conclusion: Although no significant difference was found between the groups in terms of NLR, CRP/albumin ratio and RDW levels, PLR was significantly higher in the KC group.Keywords
This publication has 22 references indexed in Scilit:
- Neutrophil-to-Lymphocyte Ratio May Predict Progression in Patients With KeratoconusCornea, 2014
- Preoperative platelet lymphocyte ratio (PLR) is superior to neutrophil lymphocyte ratio (NLR) as a predictive factor in patients with esophageal squamous cell carcinomaWorld Journal of Surgical Oncology, 2014
- Increased systemic oxidative stress in patients with keratoconusEye, 2013
- The Interleukin-1 Family: Back to the FutureImmunity, 2013
- Neutrophil-to-Lymphocyte Ratio as a Quick and Reliable Predictive Marker to Diagnose the Severity of Diabetic RetinopathyDiabetes Technology & Therapeutics, 2013
- Effects of eye rubbing on the levels of protease, protease activity and cytokines in tears: relevance in keratoconusClinical and Experimental Optometry, 2013
- ReviewCornea, 2012
- Noninflammatory Ectatic DisordersPublished by Elsevier BV ,2011
- Inflammatory Molecules in the Tears of Patients with KeratoconusOphthalmology, 2005
- KeratoconusSurvey of Ophthalmology, 1998