Changing Trends in Hospital Admissions for Pulmonary Embolism in Spain from 2001 to 2018
Open Access
- 7 October 2020
- journal article
- research article
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 9 (10), 3221
- https://doi.org/10.3390/jcm9103221
Abstract
(1) Background: The aims of this study were to examine trends in the incidence, clinical characteristics, and in-hospital outcomes of patients hospitalized with pulmonary embolism in Spain and to identify factors associated with in-hospital mortality (IHM). (2) Methods: We included all patients who were hospitalized for pulmonary embolism between 2001 and 2018. Data were collected from the Spanish National Hospital Discharge Database. (3) Results: We identified 241,821 hospitalizations for pulmonary embolism during the study period. The incidence of pulmonary embolism increased from 20.49 cases per 100,000 inhabitants in the period 2001–2002 to 35.9 cases in the period 2017–2018 (p < 0.001). After controlling for possible confounders, there was a significant increase in the incidence over the study period (adjusted incidence rate ratio 1.53, 95% Confidence Interval I 1.51–1.56). The median length of hospital stay was 11 days in the period 2001–2002, decreasing to seven days in the period 2017–2018 (p < 0.001). For the total time period, the crude IHM rate was 9.51%. After multivariable adjustment, IHM decreased significantly over time. The IHM was significantly higher in women, in patients suffering from more comorbidities, and in those with a massive pulmonary embolism. (4) Conclusions: Our results revealed an increase in the incidence of pulmonary embolism hospitalizations from 2001 to 2018 in Spain, with older patients being the most affected.Keywords
This publication has 39 references indexed in Scilit:
- National Trends in Pulmonary Embolism Hospitalization Rates and Outcomes for Adults Aged ≥65 Years in the United States (1999 to 2010)The American Journal of Cardiology, 2015
- National trends in emergency room diagnosis of pulmonary embolism, 2001–2010: a cross-sectional studyRespiratory Research, 2015
- Trends in hospital admissions for pulmonary embolism in Spain from 2002 to 2011European Respiratory Journal, 2014
- Cancer-associated unsuspected pulmonary embolismThrombosis Research, 2014
- U.S. Trends in Computed Tomography Use and Diagnoses in Emergency Department Visits by Patients With Symptoms Suggestive of Pulmonary Embolism, 2001–2009Academic Emergency Medicine, 2013
- Trends in case fatality rate in pulmonary embolism according to stability and treatmentThrombosis Research, 2012
- Obesity and pulmonary embolism: The mounting evidence of risk and the mortality paradoxThrombosis Research, 2011
- Time Trends in Pulmonary Embolism in the United StatesJAMA Internal Medicine, 2011
- Evaluation of the predictive value of ICD-9-CM coded administrative data for venous thromboembolism in the United StatesThrombosis Research, 2010
- Fibrinolytic response to venous occlusion in healthy subjects: Relationship to age, gender, body weight, blood lipids and insulinThrombosis Research, 1993