Analysis of 472,688 Severe Cases of COVID-19 in Brazil Showed Lower Mortality in Those Vaccinated against Influenza
Open Access
- 1 January 2021
- journal article
- research article
- Published by Scientific Research Publishing, Inc. in World Journal of Vaccines
- Vol. 11 (03), 28-32
- https://doi.org/10.4236/wjv.2021.113004
Abstract
Objective: To analyze the severe cases of COVID-19 in Brazil in 2020 and compare those vaccinated and unvaccinated against influenza in invasive ventilation, admission in Intensive Care Unit (ICU) and deaths. Method: Cross-sectional study with public data from the OpenDataSUS platform, regarding confirmed severe cases for COVID-19 in Brazil in the year 2020. Data were analyzed by SPSS, from the chi-square test of independence and binary logistic regression. Results: The population was 472,688 cases and 177,640 deaths, with a lethality of 37.58% in severe cases. The test of independence was highly significant in vaccinated survivors (<0.0001), and regression showed an almost twofold odds ratio for invasive ventilation, ICU admission, and death in unvaccinated cases. Conclusion: We recommend mass influenza vaccination as an adjuvant in combating the COVID-19 pandemic in Brazil.Keywords
This publication has 9 references indexed in Scilit:
- Association between influenza vaccination and hospitalisation or all-cause mortality in people with COVID-19: a retrospective cohort studyBMJ Open Respiratory Research, 2021
- Influenza Vaccination and Hospitalizations Among COVID-19 Infected AdultsThe Journal of the American Board of Family Medicine, 2021
- Inactivated trivalent influenza vaccination is associated with lower mortality among patients with COVID-19 in BrazilBMJ Evidence-Based Medicine, 2020
- Can influenza vaccine modify COVID-19 clinical course?Travel Medicine and Infectious Disease, 2020
- Epidemiological evidence for association between higher influenza vaccine uptake in the elderly and lower COVID‐19 deaths in ItalyJournal of Medical Virology, 2020
- Is BCG vaccination causally related to reduced COVID‐19 mortality?EMBO Molecular Medicine, 2020
- BCG-induced trained immunity: can it offer protection against COVID-19?Nature Reviews Immunology, 2020
- The possible beneficial adjuvant effect of influenza vaccine to minimize the severity of COVID-19Medical Hypotheses, 2020
- Randomized Trial of BCG Vaccination at Birth to Low-Birth-Weight Children: Beneficial Nonspecific Effects in the Neonatal Period?The Journal of Infectious Diseases, 2011