The Association between Depression and Suicidal Ideation A Systematic Review and Meta-Analysis

Abstract

The purpose of this meta-analysis was to assess the association between Depression and suicidal ideation. We use data from six studies to do a meta-analysis. We applied the random-effects analytic model and calculated a pooled odds ratio. The combined effect size showed that odds of suicidal ideation among people with Depression is 4.88 times higher than those peoples without Depression (ORMH 4.88 95%CI 2.04, 11.72) Test for overall effect: Z = 3.55 (P = 0.0004) Heterogeneity: Tau² = 1.11; Chi² = 100.97, df = 5 (P < 0.00001); I² = 95%. The magnitude of suicidal ideation among people with Depression is 46.39% (528) and peoples without Depression is 17.79 % (315) from the total, 39.13 % (1138) is depressed and 60.86% (1779) not depressed. The overall proportion of Suicidal Ideation among the included studies is 28.98 % (843). The total number of study subjects included in our systematic review and meta-analysis is 2908.