Degree of right ventricular dysfunction dictates outcomes after tricuspid valve repair concomitant with left-side valve surgery
- 1 June 2021
- journal article
- research article
- Published by Springer Science and Business Media LLC in General Thoracic and Cardiovascular Surgery
- Vol. 69 (6), 911-918
- https://doi.org/10.1007/s11748-020-01536-7
Abstract
Objectives The effect of different degrees of right ventricular (RV) dysfunction on long-term outcomes after tricuspid valve repair is the subject of ongoing research. We sought to evaluate the effect of preoperative RV dysfunction on mortality and recurrence of tricuspid regurgitation (TR) after tricuspid valve repair for secondary TR concomitant with left-side valve surgery. Methods This is a retrospective study, including 548 patients who underwent repair of secondary TR (2009-2017) at a single institution. Patients were grouped according to preoperative right ventricular (RV) systolic function into three groups; normal RV function (group 1, n = 451), mild RV dysfunction (group 2, n = 60) and moderate/severe RV dysfunction (group 3, n = 37). Study endpoints were mortality and recurrence of TR. Results Group 3 was associated with the highest hospital mortality (10.2%, p = .06). Predictors of moderate or higher grade TR were NYHA class (HR 2.1, p = 0.03); preoperative TR grade (HR 1.9, p < 0.01), mild RV dysfunction (HR 2.4, p < 0.01), isolated RV dilatation (HR 2.0, p < 0.01), and flexible TV repair prostheses (HR 2.4, p = 0.01). Predictors of mortality were renal impairment (HR 3.0, p < 0.01), ejection fraction (HR 0.97, p = 0.02), pulmonary artery systolic pressure (HR 1.02, p = 0.02), preoperative TR grade (HR 1.7, p < 0.01), and moderate/severe RV dysfunction (HR 3.1, p = 0.01). Conclusion Compared to normal and mild degree of RV dysfunction, moderate and severe RV dysfunction were independent predictors of poor long-term survival. Isolated RV dilatation increased the recurrence of TR. RV dysfunction and dilatation could be indications of tricuspid valve repair.This publication has 23 references indexed in Scilit:
- Right Ventricular Dysfunction, But Not Tricuspid Regurgitation, Is Associated With Outcome Late After Left Heart Valve ProcedureJournal of the American College of Cardiology, 2014
- 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: Executive SummaryCirculation, 2014
- Understanding right ventricular dysfunction and functional tricuspid regurgitation accompanying mitral valve diseaseThe Journal of Thoracic and Cardiovascular Surgery, 2013
- Accuracy and Interobserver Concordance of Echocardiographic Assessment of Right Ventricular Size and Systolic Function: A Quality Control ExerciseJournal of the American Society of Echocardiography, 2012
- Guidelines for the Echocardiographic Assessment of the Right Heart in Adults: A Report from the American Society of Echocardiography: Endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of EchocardiographyJournal of the American Society of Echocardiography, 2010
- The Tricuspid ValveCirculation, 2009
- Right Ventricular Myocardial Performance Index Predicts Perioperative Mortality or Circulatory Failure in High-Risk Valvular SurgeryJournal of the American Society of Echocardiography, 2007
- Prediction of Outcome in Patients Undergoing Surgery for Severe Tricuspid Regurgitation Following Mitral Valve Surgery and Role of Tricuspid Annular Systolic VelocityThe American Journal of Cardiology, 2006
- Secondary Tricuspid Regurgitation or Dilatation: Which Should Be the Criteria for Surgical Repair?The Annals of Thoracic Surgery, 2005
- Impact of tricuspid regurgitation on long-term survivalJournal of the American College of Cardiology, 2004