Transmission Potential of Asymptomatic and Paucisymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 Infections: A 3-Family Cluster Study in China
Open Access
- 22 April 2020
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Infectious Diseases
- Vol. 221 (12), 1948-1952
- https://doi.org/10.1093/infdis/jiaa206
Abstract
Data concerning the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in asymptomatic and paucisymptomatic patients are lacking. We report a 3-family cluster of infections involving asymptomatic and paucisymptomatic transmission. Eight of 15 (53%) members from 3 families were confirmed with SARS-CoV-2 infection. Of 8 patients, 3 were asymptomatic and 1 was paucisymptomatic. An asymptomatic mother transmitted the virus to her son, and a paucisymptomatic father transmitted the virus to his 3-month-old daughter. SARS-CoV-2 was detected in the environment of 1 household. The complete genomes of SARS-CoV-2 from the patients were > 99.9% identical and were clustered with other SARS-CoV-2 sequences reported from China and other countries.Keywords
Funding Information
- Special National Project on Investigation of Basic Resources of China (SQ2019FY010009)
- National Major Project for Control and Prevention of Infectious Disease of China (2017ZX10303401-006)
- Key Technology Research and Development Program of Shandong (2020SFXGFY02)
- National Natural Science Foundation of China (81773494, 81621005)
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