A Dynamic Data Correction Method for Enhancing Resolving Power of Integrated Spectra in Spectroscopic Analysis
- 8 September 2020
- journal article
- research article
- Published by American Chemical Society (ACS) in Analytical Chemistry
- Vol. 92 (19), 12763-12768
- https://doi.org/10.1021/acs.analchem.0c00737
Abstract
A dynamic data correction method embedded in the process of data acquisition improves spectral quality. The method minimizes the impact of random errors in spectroscopic measurements by correcting peak positions in every single-scan spectrum. The method is fast enough to facilitate on-line data correction. Integration of corrected spectra improves resolving power and signal-to-noise ratio. The correction method can apply to most analytical spectra. In mass spectrometry and Raman spectroscopy, observations show that it improved the average resolving power by roughly 40 – 150% and revealed unresolved spectral features.Keywords
Funding Information
- Academia Sinica
- Ministry of Science and Technology, Taiwan (108-2113-M-001-005)
This publication has 19 references indexed in Scilit:
- A PEAK ALIGNMENT ALGORITHM WITH NOVEL IMPROVEMENTS IN APPLICATION TO ELECTROPHEROGRAM ANALYSISJournal of Bioinformatics and Computational Biology, 2013
- icoshift: A versatile tool for the rapid alignment of 1D NMR spectraJournal of Magnetic Resonance, 2010
- Precision enhancement of MALDI‐TOF MS using high resolution peak detection and label‐free alignmentProteomics, 2008
- Automated alignment of chromatographic dataJournal of Chemometrics, 2006
- A comparison of three algorithms for chromatograms alignmentJournal of Chromatography A, 2006
- Application of Fast Fourier Transform Cross-Correlation for the Alignment of Large Chromatographic and Spectral DatasetsAnalytical Chemistry, 2005
- A methodology for automated comparative analysis of metabolite profiling dataZeitschrift für Lebensmittel-Untersuchung und Forschung, 2003
- Objective Data Alignment and Chemometric Analysis of Comprehensive Two-Dimensional Separations with Run-to-Run Peak Shifting on Both DimensionsAnalytical Chemistry, 2001
- Standardization of Second-Order Chromatographic/Spectroscopic Data for Optimum Chemical AnalysisAnalytical Chemistry, 1998
- Random errors in analytical methodsThe Analyst, 1984