Discrepancy of Microglia Activation in Acute Ischemic Stroke and Chronic Cerebral Hypoperfusion

Abstract

Acute ischemic stroke and chronic cerebral hypoperfusion share some common pathological changes and mechanisms. Inflammation plays an important rolein both acute and chronic cerebral ischemia.Microglia represent the immune system of the mammalian brain and are critically involved in cerebral ischemia, whichis an exciting target for future therapies.