One-pot multicomponent route to propargylamines using ferric hydrogensulfate
Open Access
- 31 March 2011
- journal article
- Published by European Journal of Chemistry in European Journal of Chemistry
- Vol. 2 (1), 100-103
- https://doi.org/10.5155/eurjchem.2.1.100-103.175
Abstract
The one-pot three-component coupling reaction of phenylacetylene, aldehyde and amine derivatives in the presence of ferric hydrogensulfate, [(Fe(HSO4)3], as an efficient heterogeneous catalyst is reported. The catalyst displayed high activity and afforded the corresponding propargylamines in good to excellent yields. This method provides the wide range of substrate applicability. Heterogeneous nature of the catalyst made it reusable for further chemical reactions.Keywords
This publication has 38 references indexed in Scilit:
- Three‐Component Enantioselective Synthesis of Propargylamines through Zr‐Catalyzed Additions of Alkyl Zinc Reagents to AlkynyliminesAngewandte Chemie, 2003
- Indium-mediated propargylation of imines and imine oxides in aqueous media: propargylation of CN- centresTetrahedron Letters, 2003
- Catalytic, Three-Component Assembly Reaction for the Synthesis of PyrrolidinesOrganic Letters, 2003
- Enantioselective Synthesis of Propargylamines through Zr-Catalyzed Addition of Mixed Alkynylzinc Reagents to AryliminesOrganic Letters, 2003
- Stereoselective Barbier-Type Allylation Reaction of Trifluoromethyl AldiminesThe Journal of Organic Chemistry, 2003
- N-tert-Butanesulfinyl Imines: Versatile Intermediates for the Asymmetric Synthesis of AminesAccounts of Chemical Research, 2002
- Synthetic studies of yessotoxin, a polycyclic ether implicated in diarrhetic shellfish poisoning: convergent synthesis of the BCDE ring system via an alkyne intermediateTetrahedron, 2002
- Chiral copper (ii) complexes as Lewis acids for catalyzed cycloaddition, carbonyl addition, and conjugate addition reactionsPure and Applied Chemistry, 1999
- Catalytic Enantioselective Addition to IminesChemical Reviews, 1999
- Additions of Organometallic Reagents to CN Bonds: Reactivity and SelectivityChemical Reviews, 1998