Mildly elevated liver enzymes have been reported in dengue infection. Malaria destroys the liver tissue and the enzymes are elevated in blood that is absorbed partially or fully in the blood stream. The liver enzymes in malaria are elevated in early malaria infection and it’s a rule and natural history of the disease. The enzymes can be used as a predictor for assessing the disease severity and higher the levels of liver enzymes poorer is the prognosis of the disease. Most of the studies showed that unlike other viral infections, in dengue the rise of SGOT is usually more than SGPT and is believed to be due to release from the damaged myocytes. In view of this biochemical pattern, it is possible to confuse liver involvement in malaria infection with typical acute viral hepatitis, especially in countries where outbreaks of hepatitis A and E are common. So an attempt has been made to study the hepatic enzyme values and whether it reflects the prognosis is checked in this study.