Quantification of Liver Fibrosis—A Comparative Study
Open Access
- 8 January 2020
- journal article
- review article
- Published by MDPI AG in Applied Sciences
- Vol. 10 (2), 447
- https://doi.org/10.3390/app10020447
Abstract
Liver disease has been targeted as the fifth most common cause of death worldwide and tends to steadily rise. In the last three decades, several publications focused on the quantification of liver fibrosis by means of the estimation of the collagen proportional area (CPA) in liver biopsies obtained from digital image analysis (DIA). In this paper, early and recent studies on this topic have been reviewed according to these research aims: the datasets used for the analysis, the employed image processing techniques, the obtained results, and the derived conclusions. The purpose is to identify the major strengths and “gray-areas” in the landscape of this topic.This publication has 62 references indexed in Scilit:
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