Fast periodic visual stimulation to highlight the relationship between human intracerebral recordings and scalp electroencephalography
Open Access
- 31 March 2020
- journal article
- research article
- Published by Wiley in Human Brain Mapping
- Vol. 41 (9), 2373-2388
- https://doi.org/10.1002/hbm.24952
Abstract
Despite being of primary importance for fundamental research and clinical studies, the relationship between local neural population activity and scalp electroencephalography (EEG) in humans remains largely unknown. Here we report simultaneous scalp and intracerebral EEG responses to face stimuli in a unique epileptic patient implanted with 27 intracerebral recording contacts in the right occipitotemporal cortex. The patient was shown images of faces appearing at a frequency of 6 Hz, which elicits neural responses at this exact frequency. Response quantification at this frequency allowed to objectively relate the neural activity measured inside and outside the brain. The patient exhibited typical 6 Hz responses on the scalp at the right occipitotemporal sites. Moreover, there was a clear spatial correspondence between these scalp responses and intracerebral signals in the right lateral inferior occipital gyrus, both in amplitude and in phase. Nevertheless, the signal measured on the scalp and inside the brain at nearby locations showed a 10‐fold difference in amplitude due to electrical insulation from the head. To further quantify the relationship between the scalp and intracerebral recordings, we used an approach correlating time‐varying signals at the stimulation frequency across scalp and intracerebral channels. This analysis revealed a focused and right‐lateralized correspondence between the scalp and intracerebral recordings that were specific to the face stimulation is more broadly distributed in various control situations. These results demonstrate the interest of a frequency tagging approach in characterizing the electrical propagation from brain sources to scalp EEG sensors and in identifying the cortical sources of brain functions from these recordings.Keywords
Funding Information
- Fédération Wallonie-Bruxelles (ARC 13/18‐053)
- Fondation Louvain
This publication has 70 references indexed in Scilit:
- EEG source imaging in epilepsy—practicalities and pitfallsNature Reviews Neurology, 2012
- Does rhythmic entrainment represent a generalized mechanism for organizing computation in the brain?Frontiers in Computational Neuroscience, 2012
- Robust sensitivity to facial identity in the right human occipito-temporal cortex as revealed by steady-state visual-evoked potentialsJournal of Vision, 2011
- Source localization of ictal epileptic activity investigated by high resolution EEG and validated by SEEGNeuroImage, 2010
- The Influence of Age and Skull Conductivity on Surface and Subdermal Bipolar EEG LeadsComputational Intelligence and Neuroscience, 2010
- Review on solving the inverse problem in EEG source analysisJournal of NeuroEngineering and Rehabilitation, 2008
- The neuronal sources of EEG: Modeling of simultaneous scalp and intracerebral recordings in epilepsyNeuroImage, 2008
- Effect of Skull Resistivity on the Spatial Resolutions of EEG and MEGIEEE Transactions on Biomedical Engineering, 2004
- EEG alpha and theta oscillations reflect cognitive and memory performance: a review and analysisBrain Research Reviews, 1999
- Brain Rhythms*Nature, 1944