Global, regional and national burden of osteoarthritis 1990-2017: a systematic analysis of the Global Burden of Disease Study 2017
Top Cited Papers
Open Access
- 12 May 2020
- journal article
- research article
- Published by BMJ in Annals Of The Rheumatic Diseases
- Vol. 79 (6), 819-828
- https://doi.org/10.1136/annrheumdis-2019-216515
Abstract
Objectives To report the level and trends of prevalence, incidence and years lived with disability (YLDs) for osteoarthritis (OA) in 195 countries and territories from 1990 to 2017 by age, sex and Socio-demographic index (SDI; a composite of sociodemographic factors). Methods Publicly available modelled data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 were used. The burden of OA was estimated for 195 countries and territories from 1990 to 2017, through a systematic analysis of prevalence and incidence modelled data using the methods reported in the GBD 2017 Study. All estimates were presented as counts and age-standardised rates per 100 000 population, with uncertainty intervals (UIs). Results Globally, the age-standardised point prevalence and annual incidence rate of OA in 2017 were 3754.2 (95% UI 3389.4 to 4187.6) and 181.2 (95% UI 162.6 to 202.4) per 100 000, an increase of 9.3% (95% UI 8% to 10.7%) and 8.2% (95% UI 7.1% to 9.4%) from 1990, respectively. In addition, global age-standardised YLD rate in 2017 was 118.8 (95% UI 59.5 to 236.2), an increase of 9.6% (95% UI 8.3% to 11.1%) from 1990. The global prevalence was higher in women and increased with age, peaking at the >95 age group among women and men in 2017. Generally, a positive association was found between the age-standardised YLD rate and SDI at the regional and national levels. Age-standardised prevalence of OA in 2017 ranged from 2090.3 to 6128.1 cases per 100 000 population. United States (6128.1 (95% UI 5729.3 to 6582.9)), American Samoa (5281 (95% UI 4688 to 5965.9)) and Kuwait (5234.6 (95% UI 4643.2 to 5953.6)) had the three highest levels of age-standardised prevalence. Oman (29.6% (95% UI 24.8% to 34.9%)), Equatorial Guinea (28.6% (95% UI 24.4% to 33.7%)) and the United States 23.2% (95% UI 16.4% to 30.5%)) showed the highest increase in the age-standardised prevalence during 1990–2017. Conclusions OA is a major public health challenge. While there is remarkable international variation in the prevalence, incidence and YLDs due to OA, the burden is increasing in most countries. It is expected to continue with increased life expectancy and ageing of the global population. Improving population and policy maker awareness of risk factors, including overweight and injury, and the importance and benefits of management of OA, together with providing health services for an increasing number of people living with OA, are recommended for management of the future burden of this condition.Keywords
Funding Information
- Social Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran (20607)
This publication has 25 references indexed in Scilit:
- The individual and socioeconomic impact of osteoarthritisNature Reviews Rheumatology, 2014
- The global burden of hip and knee osteoarthritis: estimates from the Global Burden of Disease 2010 studyAnnals Of The Rheumatic Diseases, 2014
- Incidence and risk factors for clinically diagnosed knee, hip and hand osteoarthritis: influences of age, gender and osteoarthritis affecting other jointsAnnals Of The Rheumatic Diseases, 2013
- Epidemiology and burden of osteoarthritisBritish Medical Bulletin, 2013
- Body mass index and susceptibility to knee osteoarthritis: A systematic review and meta-analysisJoint Bone Spine, 2012
- The epidemiology of osteoarthritis in AsiaInternational Journal of Rheumatic Diseases, 2011
- The relationship between body mass index and hip osteoarthritis: A systematic review and meta-analysisJoint Bone Spine, 2011
- Comparing the performance of the EQ-5D and SF-6D when measuring the benefits of alleviating knee painCost Effectiveness and Resource Allocation, 2009
- Cutpoints for mild, moderate and severe pain in patients with osteoarthritis of the hip or knee ready for joint replacement surgeryBMC Musculoskeletal Disorders, 2008
- Radiological Assessment of Osteo-ArthrosisAnnals Of The Rheumatic Diseases, 1957