An Association between Lower Extremity Function and Cognitive Frailty: A Sample Population from the KFACS Study
Open Access
- 23 January 2021
- journal article
- research article
- Published by MDPI AG in International Journal of Environmental Research and Public Health
- Vol. 18 (3), 1007
- https://doi.org/10.3390/ijerph18031007
Abstract
The present study aimed to define the physical function and lipid profile for physical and cognitive frailty in community-dwelling Korean older adults. A total of 229 participants (age = 76.76 ± 3.72 years; body mass index = 24.83 ± 3.15) were classified into four groups: robust, pre-frailty, cognitive decline, and cognitive frailty. An analysis on the four groups was performed to measure their physical and cognitive function, as well as blood biomarkers. The area under (AUC) the receiver operating characteristic curve (ROC) indicated that the 6-min Walk Test (6MWT), Timed Up and Go test (TUG), and Five Times Sit-to-Stand test (FTSS) had the potential to distinguish the capacity of an old adult to predict cognitive frailty. The 6MWT had a higher sensitivity and the TUG and FTSS tests had greater specificity. With cognitive frailty as a categorical variable, cognitive frailty status was a significant predictor of the TUG (odds ratio (OR) 2.897; 95% confidence interval (CI), 1.283–6.541), FTSS (OR 3.337; 95% CI 1.451–7.673), and 6MWT (OR 0.204; 95% CI 0.070–0.591) tests. Our findings indicate that the 6MWT, TUG, and FTSS tests are closely related to cognitive frailty and can provide potential prognostic cutoff points.Funding Information
- Ministry of Health and Welfare (HI15C3207)
This publication has 33 references indexed in Scilit:
- Nutritional intervention and physical training in malnourished frail community-dwelling elderly persons carried out by trained lay “buddies”: study protocol of a randomized controlled trialBMC Public Health, 2013
- Frailty Consensus: A Call to ActionJournal of the American Medical Directors Association, 2013
- Desempenho motor de idosos do Nordeste brasileiro: diferenças entre idade e sexoRevista da Escola de Enfermagem da USP, 2013
- The Dynamic Relationship Between Physical Function and Cognition in Longitudinal Aging CohortsEpidemiologic Reviews, 2013
- Ethnic‐Specific BMI and Waist Circumference ThresholdsObesity, 2011
- The 6-Minute Walk Test as a Predictor of Objectively Measured Aerobic Fitness in Healthy Working-Aged AdultsThe Physician and Sportsmedicine, 2011
- Korean Version of Mini Mental Status Examination for Dementia Screening and Its' Short FormPsychiatry Investigation, 2010
- Appropriateness of waist circumference and waist-to-hip ratio cutoffs for different ethnic groupsEuropean Journal of Clinical Nutrition, 2009
- Serum High-Density Lipoprotein Cholesterol Levels and Mortality in Frail, Community-Living ElderlyGerontology, 2007
- Gait slowing as a predictor of incident dementia: 6-year longitudinal data from the Sydney Older Persons StudyJournal of the Neurological Sciences, 2005