Health Status after Invasive or Conservative Care in Coronary and Advanced Kidney Disease

Abstract

In the ISCHEMIA-CKD trial, the primary analysis showed no significant difference in the risk of death or myocardial infarction with initial angiography and revascularization plus guideline-based medical therapy (invasive strategy) as compared with guideline-based medical therapy alone (conservative strategy) in participants with stable ischemic heart disease, moderate or severe ischemia, and advanced chronic kidney disease (an estimated glomerular filtration rate of 2 or receipt of dialysis). A secondary objective of the trial was to assess angina-related health status.