Cross‐sectional imaging for assessing intestinal fibrosis in Crohn's disease
- 17 May 2020
- journal article
- review article
- Published by Wiley in Journal of Digestive Diseases
- Vol. 21 (6), 342-350
- https://doi.org/10.1111/1751-2980.12881
Abstract
More than 30% of Crohn's disease (CD) patients develop fibrotic strictures in the bowel as the disease progresses. Excessive deposition of extracellular matrix components in the submucosa, and smooth muscle hypertrophy/ hyperplasia are the main features of fibrosis in CD. Cross‐sectional imaging technology provides a wealth of information on the anatomy, histological composition, and physiological function, allowing for a non‐invasive and complete evaluation of associated abnormalities. This review summarizes the recent advances in and the potential technologies of cross‐sectional imaging for assessing intestinal fibrosis in CD, including ultrasound imaging, computed tomography, and magnetic resonance imaging.Keywords
Funding Information
- National Natural Science Foundation of China (81870451, 81600508, 81770654)
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