BIOCHEMICAL EVALUATION OF SALIVARY SIALIC ACID IN WOMEN UNDER DIFFERENT REPRODUCTIVE PHYSIOLOGICAL CONDITIONS

Abstract

In human female reproductive physiology predicting ovulation is the basis on which the fertile period is determined. The present study was designed to investigate the level of salivary Sialic acid to find the possibility to develop a biomarker for detection of ovulation by non-invasive method. 42 females of different age group of different reproductive physiological conditions (i.e. prepubertal, parous, non-parous, menopausal, and diabetogenic) were selected for this study. It was observed significant (p<0.001) increase in ovulatory, menopause and diabetic condition and highly significant decrease in non-parous ovulatory and post ovulatory condition in women. The study showed that salivary Sialic acid concentration was elevated during ovulation.