Dramatic increase in volume versus length of invasive ductal carcinoma mimicking intramammary lymph node in a small nodular lesion
Open Access
- 12 May 2022
- journal article
- case report
- Published by Springer Science and Business Media LLC in Bulletin of the National Research Centre
- Vol. 46 (1), 1-5
- https://doi.org/10.1186/s42269-022-00823-y
Abstract
The tumor growth pattern in breast cancer appears to be variable and unpredictable. A minor increase in size in a pre-existing lesion, especially under 1 cm, corresponds to a more pronounced increase in volume. We report a 63-year-old woman with a nodular density mimicking intramammary lymph node, diagnosed as invasive carcinoma of luminal B subtype. The lesion increased size and density over time in following mammograms until having indistinct margins. While the tumor volume was 12.7 mm3 at the first observation on mammography, it has increased approximately 6.7 times to reach 85.7 mm3 in four years. Finally, the patient diagnosed with early-stage breast cancer (T1N0M0) was treated with breast-conserving surgery. Minor changes in size, density, and margin status of a lesion on serial mammograms are warning for breast cancer. Withal, a slight increase in lesion size in two dimensions can result in significant differences in volume. Therefore, comparative evaluation with previous mammograms and observing any difference in morphological features by screening are crucial for early diagnosis and optimal management of the disease.Keywords
This publication has 13 references indexed in Scilit:
- Intramammary lymph nodes: normal and abnormal multimodality imaging featuresThe British Journal of Radiology, 2019
- Breast cancer survival and prognosis by screening historyBritish Journal of Cancer, 2013
- Estimation of rat mammary tumor volume using caliper and ultrasonography measurementsLab Animal, 2013
- Long-term prognosis of breast cancer detected by mammography screening or other methodsBreast Cancer Research, 2011
- The Mammographic Density of a Mass Is a Significant Predictor of Breast CancerRadiology, 2011
- The randomized trials of breast cancer screening: what have we learned?Radiologic Clinics of North America, 2004
- Gauging the impact of breast carcinoma screening in terms of tumor size and death rateCancer, 2003
- American Cancer Society Guidelines for Breast Cancer Screening: Update 2003CA: A Cancer Journal for Clinicians, 2003
- THE SWEDISH TWO-COUNTY TRIAL TWENTY YEARS LATER: Updated Mortality Results and New Insights from Long-Term Follow-upRadiologic Clinics of North America, 2000
- In Vivo Estimation of Size of Experimental TumorsJNCI Journal of the National Cancer Institute, 1983