A Nomogram for Predicting Cancer-Specific Survival of Patients with Gastrointestinal Stromal Tumors
- 25 May 2020
- journal article
- research article
- Published by International Scientific Information, Inc. in Medical Science Monitor
- Vol. 26, e922378
- https://doi.org/10.12659/MSM.922378
Abstract
Background: The aim of this study was to construct a nomogram to predict the prognosis of patients with gastrointestinal stromal tumor (GIST). Material/Methods: We enrolled 4086 GIST patients listed in the SEER database from 1998 to 2015. They were separated to 2 groups: an experimental group (n=2862) and a verification group (n=1224). A nomogram was constructed by using statistically significant prognostic factors. Result: A nomogram that included age, sex, marital status, tumor location, grade, SEER stage, tumor size, and surgical management was developed. It can be used to predict overall survival (OS), while adding MCC 7th TNM stage can predict cancer-specific survival (CSS). The C-index used to forecast OS and CSS nomograms was 0.778 (95% CI, 0.76-0.79) and 0.818 (95% CI, 0.80-0.84), respectively. Conclusions: The nomogram can effectively predict 3- and 5-year CSS in patients with GIST, and its use can improve clinical practice.This publication has 23 references indexed in Scilit:
- Gastrointestinal Stromal TumorsGastroenterology Clinics of North America, 2013
- Risk of recurrence of gastrointestinal stromal tumour after surgery: an analysis of pooled population-based cohortsThe Lancet Oncology, 2012
- Heuristic and linear models of judgment: Matching rules and environments.Psychological Review, 2007
- Game relativity: How context influences strategic decision making.Journal of Experimental Psychology: Learning, Memory, and Cognition, 2006
- Cancer Patients' Desires for Communication of Prognosis InformationHealth Communication, 2002
- DISCLOSURE PREFERENCES ABOUT TERMINAL ILLNESS: AN EXAMINATION OF DECISION-RELATED FACTORSDeath Studies, 2002
- Women’s preferences for discussion of prognosis in early breast cancerHealth Expectations, 2001
- Information Needs and Preferences for Participation in Treatment Decisions Among Swedish Breast Cancer PatientsActa Oncologica, 2000
- Respecting the autonomy of cancer patients when talking with their families: qualitative analysis of semistructured interviews with patientsBMJ, 1996
- Disclosing the cancer diagnosis. Procedures that influence patient hopefulnessCancer, 1993