Cerebellopontine Angle Primary Choroid Plexus Carcinoma Present in an Adult: Case Report and Literature Review
Open Access
- 10 February 2021
- journal article
- review article
- Published by Springer Science and Business Media LLC in Cureus
- Vol. 13 (2)
- https://doi.org/10.7759/cureus.13268
Abstract
Choroid plexus tumors (CPTs) are rare intraventricular neoplasms that primarily occur in children and are rare in adults. Of the CPT subtypes, choroid plexus carcinomas (CPC) are highly aggressive and malignant and of World Health Organization (WHO) Grade III. Dissemination through the cerebrospinal fluid space is the inevitable natural course of the disease. In this case report, we present a 33-year-old female with a past medical history notable for schizophrenia and bipolar disease who suffered from left-sided acute vision loss and hearing loss. Magnetic resonance imaging (MRI) demonstrated multiple enhancing masses found in the left cerehellopontine angle (CPA), right internal auditory canal, the atrium of the left ventricle, and the left foramen of Monroe. After surgical decompression of the CPA tumor, the permanent final pathology was consistent with CPC. To our knowledge, this is the first reported case of a primary CPC occurring within the CPA in an adult. The unique presentation and progression of this rare adult-onset CPC provide insight for the diagnosis and treatment of other rare instances of CPTs.This publication has 19 references indexed in Scilit:
- Response to combined radiotherapy and chemotherapy of a leptomeningeal spread from choroid plexus carcinoma: case reportNeurological Sciences, 2014
- Choroid Plexus Carcinoma: A Rare Tumor in AdultSurgical Science, 2014
- Current management of choroid plexus carcinomasNeurosurgical Review, 2013
- Recurrent Adult Choroid Plexus Carcinoma Treated with High-Dose Chemotherapy and Syngeneic Stem Cell (Bone Marrow) TransplantJournal of Neurological Surgery Part A: Central European Neurosurgery, 2013
- Choroid plexus carcinoma: Case report and review of literatureJournal of Pediatric Neurosciences, 2012
- Choroid plexus carcinoma in an adultJournal of Neurosciences in Rural Practice, 2012
- SUPRATENTORIAL, EXTRAVENTRICULAR CHOROID PLEXUS CARCINOMA IN AN ADULTNeurosurgery, 2009
- Chemotherapy improves the survival of patients with choroid plexus carcinoma: a meta-analysis of individual cases with choroid plexus tumorsJournal of Neuro-Oncology, 2007
- Choroid Plexus Carcinoma Secreting Carbohydrate Antigen 19-9 in an Adult-Case Report-Neurologia medico-chirurgica, 2006
- A case of papillary adenocarcinoma of the choroid plexusThe Journal of Pathology, 1969