Suppressor of cytokine signalling-2 controls hepatic gluconeogenesis and hyperglycemia by modulating JAK2/STAT5 signalling pathway
- 28 June 2021
- journal article
- research article
- Published by Elsevier BV in Metabolism
- Vol. 122, 154823
- https://doi.org/10.1016/j.metabol.2021.154823
Abstract
No abstract availableKeywords
This publication has 38 references indexed in Scilit:
- Molecular mechanism of action of metformin: old or new insights?Diabetologia, 2013
- Hepatitis C Virus Induced a Novel Apoptosis-Like Death of Pancreatic Beta Cells through a Caspase 3-Dependent PathwayPLOS ONE, 2012
- STAT5A-Mediated SOCS2 Expression Regulates Jak2 and STAT3 Activity Following c-Src Inhibition in Head and Neck Squamous CarcinomaClinical Cancer Research, 2012
- Suppressor of Cytokine Signaling-3 Is a Glucagon-inducible Inhibitor of PKA Activity and Gluconeogenic Gene Expression in HepatocytesOnline Journal of Public Health Informatics, 2010
- Metformin and Insulin Suppress Hepatic Gluconeogenesis through Phosphorylation of CREB Binding ProteinCell, 2009
- Association of single-nucleotide polymorphisms in the suppressor of cytokine signaling 2 (SOCS2) gene with type 2 diabetes in the JapaneseGenomics, 2006
- SOCS-2 interferes with myotube formation and potentiates osteoblast differentiation through upregulation of JunB in C2C12 cellsJournal of Cellular Physiology, 2006
- SOCS-1 and SOCS-3 Block Insulin Signaling by Ubiquitin-mediated Degradation of IRS1 and IRS2Online Journal of Public Health Informatics, 2002
- Suppressor of cytokine signaling 2 regulates neuronal differentiation by inhibiting growth hormone signalingNature Neuroscience, 2002
- Role of AMP-activated protein kinase in mechanism of metformin actionJCI Insight, 2001