A two years study of dioxin-like polychlorinated biphenyls (dl-PCBs) in mother's milk in Qalyubia governorate, Egypt.

Abstract
The high cost of dl-PCBs analysis using a high-resolution gas chromatography/mass spectrometry (HR-GC/MS) generally minimizes it is regular analysis studies, especially in human tissue. In this study, a survey was carried out for analysis of dl-PCBs in thirty human milk samples collected from Qalyubia governorate, Egypt (2016-2018). Significant correlations were observed between Ʃdl-PCBs (TEQ), age, and numbers of deliveries. All dl-PCBs congeners were detected in all collected samples. Besides, the non-ortho PCB congener (PCB 126) was found at elevated concentrations. The mean TEQ concentrations of non-ortho and mono-ortho PCBs in the breast milk of the primiparous mothers were 7.30 and 0.20 pgTEQg-1 lipid, respectively. On the other hand, multiparous mothers have a mean TEQ concentration for these dl-PCBs (non-ortho and mono-ortho PCBs) of 6.1 and 0.3 pg TEQ g-1 lipid, respectively. The most found dl-PCBs were PCB-118 and PCB-156, both account 64.9% from ƩPCBs concentrations without TEF. Estimation of infant daily intakes (EIDI) showed that they are at high risk of adverse effects caused by PCBs.