本实验通过将海水养殖尾水微生物处理工艺细分为好氧硝化阶段、厌氧反硝化阶段和去除COD阶段，并辅以相应的耐高盐微生物，进行海水养殖尾水处理，同时试验了耐高盐微生物对常用渔药抑菌净的耐受度。结果表明，耐高盐微生物均在5天内完成挂膜，对环境的适应能力较强；水流速和溶氧含量是限制厌氧反硝化处理效果的主要因素；各微生物对正常用量的抑菌净的耐受度较强，用药量增大会导致菌体迅速脱落；工艺细化后，尾水中氨氮、亚硝酸氮、硝酸氮、总氮、COD的去除率均达到85%以上。 In this experiment, the microbial process of mariculture tail water was divided into aerobic nitrification stage, anaerobic denitrification stage and COD removal stage, and high salt tolerant microbes selected from saline alkali land were added to treat mariculture tail water. Additionally, the tolerance of microbes to common used fishery medicine Yijunjing was test. The results showed that the film-forming of all microbes were completed within 5 days, and the adaptabilities to the environment were strong. The flow rate and dissolved oxygen content were the main factors limiting the effect of anaerobic denitrification treatment. All microbes had strong tolerance to the normal dosage of Yijunjing, but rapid abscission would occur when the dosage was increased. After refining the process, the removal rates of ammonia nitrogen, nitrite nitrogen, nitrate nitrogen, total nitrogen and COD in the tail water were all above 85%.