Desmoglein-2 modulates tumor progression and osimertinib drug resistance through the EGFR/Src/PAK1 pathway in lung adenocarcinoma
- 7 April 2020
- journal article
- research article
- Published by Elsevier BV in Cancer Letters
- Vol. 483, 46-58
- https://doi.org/10.1016/j.canlet.2020.04.001
Abstract
No abstract availableKeywords
Funding Information
- National Natural Science Foundation of China (81802299, 81502514, 81702841)
- Fundamental Research Funds for the Central Universities (3332018070)
- CAMS Innovation Fund for Medical Sciences (2016-I2M-1-001, 2017-I2M-1-005),)
- the National Key Basic Research Development Plan (2018YFC1312105)
- Shanghai Municipal Commission of Health and Family Planning Young Scientists Fund (20164Y0253)
- China Postdoctoral Science Foundation (2019M650568)
This publication has 50 references indexed in Scilit:
- PAK1 Kinase Promotes Cell Motility and Invasiveness through CRK-II Serine Phosphorylation in Non-Small Cell Lung Cancer CellsPLOS ONE, 2012
- Coadministration of Epithelial Junction Opener JO-1 Improves the Efficacy and Safety of Chemotherapeutic DrugsClinical Cancer Research, 2012
- Activation of Rac1 by Src-dependent phosphorylation of Dock180Y1811 mediates PDGFRα-stimulated glioma tumorigenesis in mice and humansJCI Insight, 2011
- Src signaling in cancer invasionJournal of Cellular Physiology, 2010
- The Role of Src in Solid TumorsThe Oncologist, 2009
- PAK signaling in oncogenesisOncogene, 2009
- Decreased expression of the adhesion molecule desmoglein-2 is associated with diffuse-type gastric carcinomaEuropean Journal of Cancer, 2006
- Rac1 Function Is Required for Src-induced TransformationJournal of Biological Chemistry, 2003
- An Oncogenic Epidermal Growth Factor Receptor Signals via a p21-activated Kinase-Caldesmon-Myosin Phosphotyrosine ComplexOnline Journal of Public Health Informatics, 2000
- Controlling Epidermal Growth Factor (EGF)-stimulated Ras Activation in Intact Cells by a Cell-permeable Peptide Mimicking Phosphorylated EGF ReceptorOnline Journal of Public Health Informatics, 1996