Contextualizing the Relevance of Antimicrobial Resistance in the Drug Prescription and Consumption Pattern of a Tertiary Level Hospital
Open Access
- 8 October 2018
- journal article
- Published by Chitkara University Publications in Journal of Multidisciplinary Research in Healthcare
- Vol. 5 (1), 25–32
- https://doi.org/10.15415/jmrh.2018.51004
Abstract
Rampant, irrational and unscientific use of antimicrobials by the healthcare practitioners is adding to the problem of antimicrobial resistance. Therefore, it is of utmost importance to evolve and implement new policies, recommence research actions and pursue steps to manage the crisis of antimicrobial resistance, which can be accomplished by a well-designed Antimicrobial Stewardship programme. A prospective observational study aiming to investigate the use of antimicrobials in Intensive Care Units by means of an AMS programme was carried out in a 400 bedded tertiary level hospital in New Delhi with 140 ICU beds. This evidence-based study looksinto the prescription and consumption of antimicrobials, specifically in the ICUs, and attempts to corelate it with the resistance pattern of antimicrobials being used. All the patients being treated with antimicrobials, admitted in the ICUs of the hospital were selected for this descriptive research. Information associated with antimicrobials including the susceptibility pattern of isolates and full dosage regime of each patient from the group was obtained by conducting daily audits for a period of five months. Among the usage of different antimicrobial categories (antibacterial, antifungal and antiviral), the resistance percentage correlation was predominantly focused on theantibacterial. However, the study suggests no conclusive direct or indirect correlation between the usage of an antibacterial (in terms of prescription and consumption) and its resistance, which itself could be a cause of concern for medical practitioners.Keywords
This publication has 8 references indexed in Scilit:
- Characteristics of Critically-Ill Patients at Two Tertiary Care Hospitals in SudanSultan Qaboos University Medical Journal, 2018
- Factors Affecting the Length of Stay in the Intensive Care Unit: Our Clinical ExperienceBioMed Research International, 2018
- In Vitro Synergistic Activity of Antimicrobial Agents in Combination against Clinical Isolates of Colistin-Resistant Acinetobacter baumanniiAntimicrobial Agents and Chemotherapy, 2016
- The Future of Antibiotics and Resistance: A Tribute to a Career of Leadership by John BartlettClinical Infectious Diseases, 2014
- Antibiotic resistance—the need for global solutionsThe Lancet Infectious Diseases, 2013
- Antimicrobial stewardship programs: methods of operation and suggested outcomesExpert Review of Anti-infective Therapy, 2012
- Antimicrobial consumption and impact of "Reserve antibiotic indent form" in an intensive care unitIndian Journal of Pharmacology, 2010
- The relationship between the volume of antimicrobial consumption in human communities and the frequency of resistanceProceedings of the National Academy of Sciences of the United States of America, 1999