Oral communication skills, especially speaking, are significant for university students’ life and future careers. Students’ participation in any successful communicative activity is based on many factors. However, some barriers can violate this communication in the classroom (linguistics, psychological, cultural, social). Detailed literature indicated that previous studies focused only on students' linguistic knowledge and ignored other factors such as social, cultural, and psychological problems. Therefore, this research investigates barriers that suffocate university students' oral communication interaction with their teachers and suggests some solutions to discard these obstacles. The study adopted a quantitative method based on a self-administered closed and open-ended questionnaire. Students were asked to tick the reasons that hinder them from communicating in the class with their teachers. The study addressed 107 third-year students at the English Department at Moulay Ismail University in Meknes, Morocco. The obtained results indicated that social barriers constituted the major challenge that hinders or blocks students from oral participation with their teachers. Next, linguistics knowledge came as a second barrier, and finally, physical barriers.