Genomic organization of a Gamma-6 papillomavirus metagenomic discovered from vaginal swab samples of Chinese pregnant women
Open Access
- 31 March 2020
- journal article
- research article
- Published by Springer Science and Business Media LLC in Virology Journal
- Vol. 17 (1), 1-6
- https://doi.org/10.1186/s12985-020-01319-9
Abstract
A complete genome sequence of human papillomaviruses (HPV) named as HPV-ujs-21015 was determined by viral metagenomic and PCR methods. The complete genome is 7354 bp in length with GC content of 41.7%, of which the genome was predicted to contain six ORFs (Open Reading Frame, ORF) coding for four early proteins (E7, E1, E4, and E2) and two late proteins (L1 and L2). Phylogenetic analysis based on the complete genome and the L1 protein showed that HPV-ujs-21015 belongs to a type 214 member within genus Gamma-6 papillomavirus. It is the first complete genome of Gamma-6 papillomavirus discovered from pregnant women in China.Keywords
Funding Information
- Changzhou Social Development Project (CE20185002)
- Jiangsu Social Development Project (BE2016663)
- Zhangjiagang science and technology planned project (ZKS1703)
- Research Funds of Jiangsu Entry-Exit Inspection and Quarantine Bureau (2018KJ07)
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