Two new pyrrolidine alkaloids from the red alga Acanthophora spicifera

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Abstract
Two new pyrrolidine alkaloids, acanthophoraines B (1) and C (2), together with five known ones (3–7) were isolated from the red alga Acanthophora spicifera. Their structures were elucidated by extensive spectroscopic methods and single-crystal X-ray diffraction analysis. The absolute configuration of 2 was established by ECD calculation. The antibacterial activities of 1–7 were also evaluated. Graphical Abstract
Funding Information
  • National Key Research and Development Plan of China (900, 905)
  • National Natural Science Foundation of China
  • Science and Technology Planning Project of Guangzhou
  • Natural Science Foundation of Guangdong Province (2)