Impact of both socioeconomic level and occupation on antibody prevalence to SARS‐CoV‐2 in an Egyptian cohort: The first episode
Open Access
- 6 February 2021
- journal article
- research article
- Published by Wiley in Journal of Medical Virology
- Vol. 93 (5), 3062-3068
- https://doi.org/10.1002/jmv.26852
Abstract
We studied the impact of socioeconomic level on the anti‐SARS‐CoV‐2‐antibodies prevalence in an Egyptian cohort. The low socioeconomic standard group (LSS) included 51 humans, 30 females (F) and 21 males (M). The high socioeconomic standard group (HSS) included 55 subjects, 24 F and 31 M. Of the 30 LSSF, 6 were immunoglobulin M (IgM), 21 immunoglobulin G (IgG), and 6 double positive. Of the 21 LSSM, 5 were IgM, 12 IgG, and 5 double positive. Of the 24 HSSF, 6 were IgM, 11 IgG, and 5 double positive. Of the 31 HSSM, 6 were IgM, 14 IgG, and 4 double positive. Of the 51 LSS humans, 26 were symptomatic (S) and 25 asymptomatic (AS). Of the 26 S, 20 were IgG and 8 IgM/IgG double positive. Of the 25 AS, 13 were IgG and 3 IgM/IgG double positive. Of the 55 HSS humans, 38 were S and 17 AS. Of the 38S, 24 were IgG and 11 IgM positive of whom, 9 were double positive. Of the 17 AS, one was IgG and one IgM positive. The IgM prevalence was higher among the HSS humans. The IgG prevalence was significantly higher among the LSS humans. In the two different socioeconomic standards, the prevalence of either IgM or IgG was higher among F. An inverse correlation was observed between age and the anti‐SARS‐CoV‐2‐antibodies prevalence except for LSSF‐IgG and LSSM‐IgM. In conclusion, socioeconomic standard, gender, and age impact humoral responses to SARS‐CoV‐2 with a clear heterogeneity in individualized responses to the infection in terms of symptoms.This publication has 27 references indexed in Scilit:
- Clinical evaluation of SARS-CoV-2 point-of-care antibody testsPathology, 2020
- Evaluation of the performance of SARS-CoV-2 serological tools and their positioning in COVID-19 diagnostic strategiesDiagnostic Microbiology and Infectious Disease, 2020
- Discordance between Serum Neutralizing Antibody Titers and the Recovery from COVID-19The Journal of Immunology, 2020
- Humoral immune responses and neutralizing antibodies against SARS-CoV-2; implications in pathogenesis and protective immunityBiochemical and Biophysical Research Communications, 2020
- SARS-CoV-2 antibody prevalence in Brazil: results from two successive nationwide serological household surveysThe Lancet. Global Health, 2020
- Clinical characteristics and humoral immune response in healthcare workers with COVID-19 in a teaching hospital in BelgiumJournal of Hospital Infection, 2020
- Novel SARS-CoV-2 specific antibody and neutralization assays reveal wide range of humoral immune response during COVID-19Published by Cold Spring Harbor Laboratory ,2020
- Convalescent plasma - Is it useful for treating SARS Co-V2 infection?Indian Journal of Medical Microbiology, 2020
- Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected PneumoniaThe New England Journal of Medicine, 2020
- Job hazards and respiratory symptoms in Hispanic female domestic cleanersArchives of Environmental & Occupational Health, 2019