ApmA Is a Unique Aminoglycoside Antibiotic Acetyltransferase That Inactivates Apramycin

Abstract
Apramycin is an aminoglycoside antibiotic that has been traditionally used in veterinary medicine. Recently, it has become an attractive candidate to repurpose in the fight against multidrug-resistant pathogens prioritized by the World Health Organization.
Funding Information
  • Ontario Research Fund
  • HHS | National Institutes of Health (HHSN272201700060C)
  • HHS | NIH | National Institute of Allergy and Infectious Diseases (HHSN272201700060C)
  • U.S. Department of Health and Human Services (HHSN272201700060C)
  • Canada Research Chairs
  • Gouvernement du Canada | Canadian Institutes of Health Research (FRN-148463)

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