The impact of an in-department pharmacist on the prevention of drug iatrogenesis in a rheumatology department
- 1 January 2021
- journal article
- research article
- Published by Springer Science and Business Media LLC in Clinical Rheumatology
- Vol. 40 (1), 359-368
- https://doi.org/10.1007/s10067-020-05138-9
Abstract
Introduction/objectives The primary objective was to evaluate the impact of an in-department pharmacist on the prevention of drug iatrogenesis in a rheumatology department. Secondary objectives were to determine (i) if medication history discrepancies were detected more frequently in the elderly or not, and (ii) if the mean number of treatments at admission had an impact on the number of medication history discrepancies. Methods Implementation of a clinical-pharmacy program based on medication reconciliation and medication review of prescription for all patients admitted to a rheumatology department between January and June 2017. The analytical approach was mainly descriptive and data were expressed as mean +/- standard deviation (i.e., number of treatments at admission, number of medication reconciliations) and as proportions (i.e., acceptance rate, impact). Chi-squared tests and Student's test were performed to determine if there was a significant difference in outcomes. Results Three hundred twelve patients were included in the study, 517 medication history discrepancies in 243 (77.8%) patients and 196 pharmaceutical interventions in 133 (42.6%) patients. A significant difference was found in the number of medication history discrepancies and pharmaceutical interventions between the two age groups and in the mean number of treatments at admission between patients with or without medication history discrepancies. 15.4% of study patients had major medication history discrepancies and major pharmaceutical interventions. All patients and practitioners reported the usefulness of an in-department pharmacist. Conclusion This program was found effective in terms of safety and improvement in the continuity of care.This publication has 29 references indexed in Scilit:
- Systemic diseases and biotherapies: Understanding, evaluating, and preventing the risk of hepatitis B reactivationJoint Bone Spine, 2014
- Acceptance and importance of clinical pharmacists’ LIMM-based recommendationsInternational Journal of Clinical Pharmacy, 2012
- Prescribing of opioid analgesics and related mortality before and after the introduction of long-acting oxycodoneCMAJ : Canadian Medical Association Journal, 2009
- Interventions that can Reduce Inappropriate Prescribing in the ElderlyDrugs & Aging, 2009
- Randomized Trial to Improve Prescribing Safety in Ambulatory Elderly PatientsJournal of the American Geriatrics Society, 2007
- Impact of the Clinical Pharmacist on Readmission in Patients with Acute Coronary SyndromeAnnals of Pharmacotherapy, 2005
- Frequency, type and clinical importance of medication history errors at admission to hospital: a systematic reviewCMAJ : Canadian Medical Association Journal, 2005
- A prospective multicentre study of pharmacist initiated changes to drug therapy and patient management in acute care government funded hospitalsBritish Journal of Clinical Pharmacology, 2004
- Investigation into the reasons for preventable drug related admissions to a medical admissions unit: observational studyQuality and Safety in Health Care, 2003
- Role of the Clinical Pharmacist in Improving Drug TherapyArchives of Internal Medicine, 1981